R'MES is a set of command-line tools to assess the exceptionality of words or families of words in biological sequences.
Using different mathematical models it gives a statistical measure of how much occurrences of words in sequences deviate from their expected values, an can thus single out words having a potential biological interest. It has already been used to prove on a statistical basis that a specific motif (called CHI) is over-represented in certain kind of bacteria. R'MES is an initiative of the Applied Mathematics and Computing division of the french Agronomical Research Institute (INRA).